Welcome to the Neonatal Neurology and Physiology Research Lab!

Work in the Neonatal Neurology and Physiology Research Lab focuses on understanding the physiologic basis for brain injury in neonates, as well as the development of new methodologies for prediction of neurologic injury. The ultimate goal of these efforts is the development of new strategies for neonatal neuroprotection. Our lab group is a multi-disciplinary team of neonatologists, neurologists, pharmacists, students (high school, undergraduate and medical) and research support staff.  We are housed in the Patient Oriented Research Unit on the tenth floor of the Northwest Tower on the Washington University Medical Center Campus.

We use large multimodality (NIRS, EEG, MRI, vital signs) datasets to develop new approaches to understanding the pathophysiology of brain injury in preterm (intraventricular hemorrhage, white matter injury, cerebellar hemorrhage) and term (hypoxic-ischemic encephalopathy) infants, as well as seizures in all neonates.

We continue to recruit new patients for observational and clinical trials. We have a strong background in clinical trials, participating in Phase II and III of the multi-center HEAL trial, SafeBoosC-III, ACT-NOW, BOx-II and MMC-SDB.

Learn more about our research …